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Petri Dish Experiment

About Us

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Founder & Scientific Advisor
Edroaldo Lummertz da Rocha, PhD

Dr. Lummertz da Rocha’s research at the intersection of biology, computational biology and artificial intelligence has contributed to advance the fields of stem cell biology and engineering as well as cancer research.

Dr. Lummertz da Rocha trained in prestigious universities, hospitals and research institutions, such as the Wyss Institute for Biologically Inspired Engineering at Harvard University, Mayo Clinic, Boston Children’s Hospital and Harvard Medical School. Dr. Lummertz da Rocha is an Assistant Professor at Federal University of Santa Catarina and Affiliate Faculty of Dell Medical School at the University of Texas in Austin. He has secured funding from the National Institutes of Health, USA, The State of Santa Catarina Research and Innovation Support Foundation (FAPESC) and the Serrapilheira Institute, Brazil, to support his laboratory’s research on hematopoiesis and cancer metastasis at the intersection with biomedical data science.

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Mission & History

Codonscope emerged from the understanding that while the mRNA sequence space holds countless possibilities, uncovering the most promising designs demands intelligent exploration. Traditional codon optimization focuses only on frequency — we go deeper. By combining deep learning and physics-based models, we’ve developed a platform that enhances protein expression, stability, and translational efficiency through intelligent, end-to-end mRNA design.

 

Developed within Cellertz Bio, Codonscope has evolved through collaborative research and experimental validation. It’s now a growing platform aimed at powering the next generation of mRNA-based therapies and synthetic biology breakthroughs.

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Publications

Nat Cell Biol. 2022 Apr.

CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development

Nature 2022

Lifelong multilineage contribution by embryonic-born blood progenitors

Cell Stem Cell 2022

EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity

JCI 2021

LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy

JEM 2019

The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia

Nature 2018

Reconstruction of complex single-cell trajectories using CellRouter

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CodonScope Technology By The Numbers

10¹²

Codonscope efficiently generates mRNA sequence variations that outperform current strategies — in minutes or hours, depending on sequence length, not millennia.

Design Possibilities

Validated data shows Codonscope-designed mRNAs produce up to 8 times more protein compared to wild-type sequences.

Higher Expression

Codonscope increases protein expression duration in both stable and RNA-degrading cellular environments.

Longer Duration

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We jointly design the 5'UTR, coding sequence, and 3'UTR — a unique triple-layer approach that boosts mRNA fitness and functionality.

Optimisation Layers

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Careers

Currently no openings

We're not hiring at the moment — but we’re always open to connecting with curious minds passionate about synthetic biology, machine learning, and therapeutic innovation. If you believe you’d be a great fit, feel free to reach out at contact@cellertz.com

San Fransisco

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